Design of an implantable active microport system for autonomous time-variant drug release

Conference: Mikrosystemtechnik Kongress 2005 - Mikrosystemtechnik Kongress 2005
10/10/2005 - 10/12/2005 at Munich, Germany

Proceedings: Mikrosystemtechnik Kongress 2005

Pages: 4Language: englishTyp: PDF

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Geipel, A.; Doll, A.; Goldschmidtböing, F.; Woias, P. (IMTEK – University of Freiburg, Laboratory for Design of Microsystems, Georges-Koehler-Allee 102, 79110 Freiburg, Germany)
Jantscheff, P.; Esser, N.; Massing, U. (Tumor Biology Center, Dept. Clinical Research, Freiburg, Germany)

The controlled release of small drug volumes is crucial for innovative methods in cancer treatment or pain therapy. We present a concept of an active microport that considerably extends the options of medical treatment since it offers the potential of an arbitrary, patient-specific release profile. For release control and detection of occlusion, a simple and economical method is demonstrated which is based on the specific properties of a pulsatile flow and utilizes one commercial pressure sensor only.