Detection of gold nanoparticles in complex matrices by SP-ICP-MS
Conference: BIBE 2018 - International Conference on Biological Information and Biomedical Engineering
06/06/2018 - 06/08/2018 at Shanghai, China
Proceedings: BIBE 2018
Pages: 5Language: englishTyp: PDF
Personal VDE Members are entitled to a 10% discount on this title
Authors:
Gong, Zishan; Sun, Chuanqiang; Yang, Ru; Sun, Yun; Jiang, Xuehui; Du, Kang; Wang, Yan (Department of Precision Instrument and Opto-Electronics Engineering, Tianjin University, 92 Weijin Road, Tianjin 300072, China)
Han, Wennian (Suzhou Biomedical Engineering Tianjiin Engineering Technology Research Institute Chinese Academy of Sciences, Tianjin 300399, China)
Abstract:
Along with the quick development of science and technology, nanotechnology has attracted much attention in recent years. A reliable method for detecting nanoparticles is necessary to evaluate their performance and effectiveness. Single particle inductively coupled plasma mass spectrometry (SP-ICP-MS) is ideal to study inorganic nanoparticles due to its element-specific detection and high sensitivity. It can quickly provide information about nanoparticle size, size distribution, particle number concentration and element composition of samples with small interference for samples. In this work, SP-ICP-MS was used to monitor the synthesis of AuNPs under different reaction conditions. At the same time, AuNPs in complex matrices of human serum was detected, and the recovery was 101.5%.