Pattern corneal cross-linking with eyeball tracking

Conference: BIBE 2019 - The Third International Conference on Biological Information and Biomedical Engineering
06/20/2019 - 06/22/2019 at Hangzhou, China

Proceedings: BIBE 2019

Pages: 7Language: englishTyp: PDF

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Authors:
Zhou, Yiming (Graduate School at Shenzhen, Tsinghua University, Shenzhen, China & Department of Mechanical Engineering, Tsinghua University, Beijing, China)
Hu, Yingbing; Chen, Yun (Graduate School at Shenzhen, Tsinghua University, Shenzhen, China & Open Faculty for Innovation, Education, Science, Technology and Art, Tsinghua University, Shenzhen, China)
Mi, Shengli (Graduate School at Shenzhen, Tsinghua University, Shenzhen, China & Department of Mechanical Engineering, Tsinghua University, Beijing, China & Open Faculty for Innovation, Education, Science, Technology and Art, Tsinghua University, Shenzhen, China)

Abstract:
Background: The standard corneal cross-linking generally illuminates a circular spot, which cannot move, and the energy distribution cannot change. By applying digital light projection technology and eyeball tracking algorithm in the new system, the tracking treatment with specific illumination patterns and energy distribution can be realized. Some animal experiments were conducted to verify the new method. Results: The elastics modulus of the cornea cross-linked with the new method increases by 82.63% (compared to the normal cornea), while the radiation power halves (compared to the standard method). Conclusion: The pattern cross-linking method reduces the ultraviolet irradiation while ensures the treatment effect. More significantly, it grants ophthalmologist the ability to provide customized treatment pattern and helps researchers study the mechanics of corneal cross-linking.