Water-soluble CuInS2/ZnS quantum dots for reactive oxygen species production

Conference: BIBE 2019 - The Third International Conference on Biological Information and Biomedical Engineering
06/20/2019 - 06/22/2019 at Hangzhou, China

Proceedings: BIBE 2019

Pages: 4Language: englishTyp: PDF

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Zhang, Beilong; Zou, Peng; Li, Jinhua; Zhang, Xinyue (International Joint Research Center for Nanophotonics and Biophotonics, Nanophotonics and Biophotonics Key Laboratory of Jilin Province, School of Science, Changchun University of Science and Technology, Changchun, China)
Wang, Xiaojun; Ma, Li (Georgia Southern University, USA)

Quantum dot (QDs) nanomaterials have many unique advantages in biological applications. In this work, water-soluble CuInS2/ZnS (ZCIS) was successfully prepared, and its production level of active oxygen species (ROS) under 532nm laser excitation was tested. The effects of illumination time and different concentrations of ZCIS QDs on ROS production and on cancer cell activity inhibition were studied. The results show that ZCIS QDs can produce ROS and inhibit the growth of breast cancer cells. Such quantum dots are expected to be used as photosensitizers and can be used in photodynamic therapy research.