TM7SF3 Is Upregulated in Cervical Cancer and Correlates with Immune Infiltration and Tumor Stemness

Abstract:
Cervical cancer stands as a prevalent malignant neoplasm within the female reproductive system. Its occurrence and development are closely related to abnormal gene expression, immune microenvironment disorders and tumor cell stemness. As a membrane protein, transmembrane 7 superfamily member 3 (TM7SF3) has been reported to be involved in cell proliferation, metastasis and immune regulation in a variety of tumors in recent years. Through bioinformatics analysis, this study explored the expression pattern of TM7SF3 in CESC and its association with clinical prognosis, immune infiltration and tumor stemness.