Integration of Nanochannels for Lab-on-Chip-Systems

Konferenz: Mikro-Nano-Integration - 6. GMM-Workshop
05.10.2016 - 06.10.2016 in Duisburg, Deutschland

Tagungsband: GMM-Fb. 86: Mikro-Nano-Integration

Seiten: 4Sprache: EnglischTyp: PDF

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Khoury, Mario El; Quednau, Sebastian; Schlaak, Helmut. F. (Department of Electrical Engineering and Information Technology, Institute of Electromechanical Design, Technische Universität Darmstadt, Merckstr. 25, 64283, Darmstadt, Germany)
Duznovic, Ivana; Ensinger, Wolfgang (Department of Materials Science, Materials Analysis, Technische Universität Darmstadt, Alarich-Weiss-Str. 2, 64287 Darmstadt, Germany)

The transport of ions and molecules across a biological membrane is regulated by biological nanochannels, which are highly selective. They are incorporated in the cellular membrane and therefore not suitable in technical systems. In this study ion-track etched synthetic nanochannels are chemically modified and used as a biosensing element. Currently, the nanochannels’ sensory function is examined in a complex laboratory setup. In this study the functionalized membranes are integrated into a lab-on-chip-system. The designed microfluidic device with integrated nanochannels and electrodes is presented. The microfluidic channels are fabricated by structuring using a dry film photoresist. A polycarbonate ion-track etched nanochannel is sandwiched between two photoresist layers using a solvent-free, low temperature bonding process.