3-D FE steady-state electrodiffusion model of Ionic Channels

Konferenz: CEM 2006 - 6th International Conference on Computational Electromagnetics
04.04.2006 - 06.04.2006 in Aachen, Germany

Tagungsband: CEM 2006

Seiten: 2Sprache: EnglischTyp: PDF

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Coco, S.; Gazzo, D. S. M.; Laudani, A.; Pollicino, G. (DIEES, University of Catania, Viale A. Doria 6, 95125 Catania, Italy)

A 3-D Finite Element steady-state electrodiffusion (poisson-Nemst-Planck) model is presented and applied to the analysis of the ion transport across ionic channels of cellular membrane. The model allows us to obtain an accurate description of ion flow across the cell membrane. An example of application to the case of a K channel is also illustrated. The resulting current-voltage curve for the K channel shows excellent agreement with experimental measurements.