Phage-based environmental nanobiosensor

Konferenz: CNNA 2016 - 15th International Workshop on Cellular Nanoscale Networks and their Applications
23.08.2016 - 25.08.2016 in Dresden, Deutschland

Tagungsband: CNNA 2016

Seiten: 2Sprache: EnglischTyp: PDF

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Autoren:
Akbar, Teuku Fawzul; Ibarlucea, Bergoi; Baraban, Larysa; Cuniberti, Gianaurelio (Institute of Materials Science and Max Bergmann Center of Biomaterials, Center for Advancing Electronics Dresden, Technische Universität Dresden, Dresden, Germany)
Rim, Taiuk; Baek, Chang Ki (Department of Creative IT Engineering, Pohang University of Science and Technology, Pohang, Korea)
Ascoli, Alon; Tetzlaff, Ronald (Fakultät Elektrotechnik und Informationstechnik, Professur für Grundlagen der Elektrotechnik, Technische Universität Dresden, Dresden, Germany)
Bodas, Dhananjay (Centre for Nanobioscience, Agharkar Research Institute, Pune, India)

Inhalt:
We demonstrate a miniaturized electronic sensing platform based on top-down fabricated silicon nanowire field effect transistors (FETs) for specific detection of Salmonella typhimurium from environmental water samples. To realize the successful detection of the bacteria we propose to use (a) the honeycomb assembly of the nanowires within a FET for better gate control and stable device performance, and (b) phage isolated peptides used as specific binding receptors.