LED actuated wax valves in lab-on-a-foil for bead-based diagnostic devices

Konferenz: Smart Systems Integration - 13th International Conference & Exhibition on Integration Issues of Miniaturized Systems
10.04.2019 - 11.04.2019 in Barcelona, Spain

Tagungsband: SmartSystems Integration

Seiten: 3Sprache: EnglischTyp: PDF

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Burdo, Mireia; Diaz-Gonzalez, Maria; Fernandez-Sanchez, Cesar; Baldi, Antoni (Grupo de Transductores Químicos, Institut de Microelectrònica de Barcelona (IMB-CNM, CSIC), Cerdanyola del Vallès, Barcelona, Spain)
Sanchis, Ana; Marco, M.-Pilar (Nanobiotechnology for diagnostics (Nb4D), Department of Chemical and Biomolecular Nanotechnology, Institute for Advanced Chemistry of Catalonia (IQAC) of the Spanish Council for Scientific Research (CSIC), Barcelona, Spain & CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Barcelona, Spain)

One of the simplest and cheapest ways to produce microfluidic devices is based on the use of cut-out double-sided tape and plastic films [1]. These so-called “lab-on-a-foil” systems are restricted to simple assays due to the lack of easily actuated integrated microvalves [2]. Multiple-actuation wax microvalves are, for the first time, integrated into lab-on-a-foil systems. These optically-actuated valves are especially suited for the implementation of bead-based ELISA-like assays. The driving instrument used to manage fluids is based on a simple array of LEDs for valve actuation.